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For several hundred years afterward, with the cultural taboo of dissection, no major progress occurred in neuroscience.

However, Pope Sixtus IV effectively revitalized the study of neuroanatomy by altering the papal policy and allowing human dissection.

Immunoreacted transcription factor proteins reveal genomic readout in terms of translated protein.

This immensely increases the capacity of researchers to distinguish between different cell types (such as neurons and glia) in various regions of the nervous system.

The first known written record of a study of the anatomy of the human brain is the ancient Egyptian document the Edwin Smith Papyrus.

The next major development in neuroanatomy came from the Greek Alcmaeon, who determined that the brain and not the heart ruled the body and that the senses were dependent on the brain.

This resulted in a boom of research in neuroanatomy by artists and scientists of the Renaissance Note that such descriptors (dorsal/ventral, rostral/caudal; medial/lateral) are relative rather than absolute (e.g., a lateral structure may be said to lie medial to something else that lies even more laterally).

Commonly used terms for planes of orientation or planes of section in neuroanatomy are "sagittal", "transverse" or "coronal", and "axial" or "horizontal".

The delineation of distinct structures and regions of the nervous system has been critical in investigating how it works.This applies importantly to molecules related to neurotransmitter production and metabolism, but applies likewise in many other directions chemoarchitecture, or chemical neuroanatomy.Immunocytochemistry is a special case of histochemistry that uses selective antibodies against a variety of chemical epitopes of the nervous system to selectively stain particular cell types, axonal fascicles, neuropiles, glial processes or blood vessels, or specific intracytoplasmic or intranuclear proteins and other immunogenetic molecules, e.g., neurotransmitters.For example, much of what neuroscientists have learned comes from observing how damage or "lesions" to specific brain areas affects behavior or other neural functions.For information about the composition of animal nervous systems, see nervous system.

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